The eosinophil responses of the dental patients, both before and after local anesthesia, were studied. Ten male subiects between 22 and 26 years of age participated. They were divided into 2 groups; group 1 & group 2.
Blood sample was taken at 10 minutes before anesthesia respectively. A second blood specimen was taken at 10minutes and 30minutes after the administration of the anesthetic.
The resultant findings were as follows :
1) In group 1 the mean variation among the 5 patients were as follow: at 10 minutes after the administration of the anesthetic, -6.43 per cent.
2) In group 2 the mean variation among the 5 patients were as follow: at 30 minutes after the administraton of the anesthetic, -16.69 per cent.
3) Sharp change in the munber of circulating eosinophils at 30 minutes after anesthesia appears to be resulted mainly from emotional fatigue and psychologic factors were of primary importance in eosinophil level with local anestheasia.
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